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Structural role of the flanking DNA in mariner transposon excision

During cut-and-paste mariner/Tc1 transposition, transposon DNA is cut precisely at its junction with flanking DNA, ensuring the transposon is neither shortened nor lengthened with each transposition event. Each transposon end is flanked by a TpA dinucleotide: the signature target site duplication of...

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Detalles Bibliográficos
Autores principales: Dornan, Jacqueline, Grey, Heather, Richardson, Julia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344528/
https://www.ncbi.nlm.nih.gov/pubmed/25662605
http://dx.doi.org/10.1093/nar/gkv096