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DNA damage response markers are differentially expressed in BRCA-mutated breast cancers

Cells have stringent DNA repair pathways that are specific for each different set of DNA lesions which is accomplished through the integration of complex array of proteins. However, BRCA-mutated breast cancer (BC) has defective DNA repair mechanisms. This study aims to investigate differential expre...

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Detalles Bibliográficos
Autores principales: Aleskandarany, Mohammed, Caracappa, Daniela, Nolan, Christopher C., Macmillan, R. Douglas, Ellis, Ian O., Rakha, Emad A., Green, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344553/
https://www.ncbi.nlm.nih.gov/pubmed/25690937
http://dx.doi.org/10.1007/s10549-015-3306-6