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Design, Synthesis and Biological Evaluation of Novel Bromophenol Derivatives Incorporating Indolin-2-One Moiety as Potential Anticancer Agents

A series of bromophenol derivatives containing indolin-2-one moiety were designed and evaluated that for their anticancer activities against A549, Bel7402, HepG2, HeLa and HCT116 cancer cell lines using MTT assay in vitro. Among them, seven compounds (4g–4i, 5h, 6d, 7a, 7b) showed potent activity ag...

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Detalles Bibliográficos
Autores principales: Wang, Li-Jun, Wang, Shuai-Yu, Jiang, Bo, Wu, Ning, Li, Xiang-Qian, Wang, Bao-Cheng, Luo, Jiao, Yang, Meng, Jin, Shui-Hua, Shi, Da-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344603/
https://www.ncbi.nlm.nih.gov/pubmed/25648512
http://dx.doi.org/10.3390/md13020806