Synthesis and Biological Evaluation of Carbocyclic Analogues of Pachastrissamine

A series of carbocyclic analogues of naturally-occurring marine sphingolipid pachastrissamine were prepared and biologically evaluated. The analogues were efficiently synthesized via a tandem enyne/diene-ene metathesis reaction as a key step. We found that the analogue 4b exhibited comparable cytoto...

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Detalles Bibliográficos
Autores principales: Kwon, Yongseok, Song, Jayoung, Bae, Hoon, Kim, Woo-Jung, Lee, Joo-Youn, Han, Geun-Hee, Lee, Sang Kook, Kim, Sanghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344604/
https://www.ncbi.nlm.nih.gov/pubmed/25654428
http://dx.doi.org/10.3390/md13020824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344604/
https://www.ncbi.nlm.nih.gov/pubmed/25654428
http://dx.doi.org/10.3390/md13020824

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