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Synthesis and Biological Evaluation of Carbocyclic Analogues of Pachastrissamine

A series of carbocyclic analogues of naturally-occurring marine sphingolipid pachastrissamine were prepared and biologically evaluated. The analogues were efficiently synthesized via a tandem enyne/diene-ene metathesis reaction as a key step. We found that the analogue 4b exhibited comparable cytoto...

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Detalles Bibliográficos
Autores principales:	Kwon, Yongseok, Song, Jayoung, Bae, Hoon, Kim, Woo-Jung, Lee, Joo-Youn, Han, Geun-Hee, Lee, Sang Kook, Kim, Sanghee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344604/ https://www.ncbi.nlm.nih.gov/pubmed/25654428 http://dx.doi.org/10.3390/md13020824

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