Selective Blocking Effects of 4,9-Anhydrotetrodotoxin, Purified from a Crude Mixture of Tetrodotoxin Analogues, on Na(V)1.6 Channels and Its Chemical Aspects

Tetrodotoxin (TTX) is a potent neurotoxin found in a number of marine creatures including the pufferfish, where it is synthesized by bacteria and accumulated through the food chain. It is a potent and selective blocker of some types of voltage-gated Na(+) channel (Na(V) channel). 4,9-Anhydrotetrodot...

Descripción completa

Detalles Bibliográficos
Autores principales: Teramoto, Noriyoshi, Yotsu-Yamashita, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344613/
https://www.ncbi.nlm.nih.gov/pubmed/25686275
http://dx.doi.org/10.3390/md13020984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344613/
https://www.ncbi.nlm.nih.gov/pubmed/25686275
http://dx.doi.org/10.3390/md13020984

Ejemplares similares