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Mutagenesis and Functional Analysis of the Pore-Forming Toxin HALT-1 from Hydra magnipapillata

Actinoporins are small 18.5 kDa pore-forming toxins. A family of six actinoporin genes has been identified in the genome of Hydra magnipapillata, and HALT-1 (Hydra actinoporin-like toxin-1) has been shown to have haemolytic activity. In this study, we have used site-directed mutagenesis to investiga...

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Detalles Bibliográficos
Autores principales: Liew, Yvonne Jing Mei, Soh, Wai Tuck, Jiemy, William Febry, Hwang, Jung Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344632/
https://www.ncbi.nlm.nih.gov/pubmed/25654788
http://dx.doi.org/10.3390/toxins7020407