The Anti-Cancer Potency and Mechanism of a Novel Tumor-Activated Fused Toxin, DLM

Melittin, which acts as a membrane-disrupting lytic peptide, is not only cytotoxic to tumors, but also vital to normal cells. Melittin had low toxicity when coupled with target peptides. Despite significant research development with the fused toxin, a new fused toxin is needed which has a cleavable...

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Detalles Bibliográficos
Autores principales: Sun, Dejun, Sun, Miaonan, Zhu, Wenhe, Wang, Zhiding, Li, Yuefei, Ma, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344633/
https://www.ncbi.nlm.nih.gov/pubmed/25658509
http://dx.doi.org/10.3390/toxins7020423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344633/
https://www.ncbi.nlm.nih.gov/pubmed/25658509
http://dx.doi.org/10.3390/toxins7020423

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