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The Anti-Cancer Potency and Mechanism of a Novel Tumor-Activated Fused Toxin, DLM
Melittin, which acts as a membrane-disrupting lytic peptide, is not only cytotoxic to tumors, but also vital to normal cells. Melittin had low toxicity when coupled with target peptides. Despite significant research development with the fused toxin, a new fused toxin is needed which has a cleavable...
Autores principales: | Sun, Dejun, Sun, Miaonan, Zhu, Wenhe, Wang, Zhiding, Li, Yuefei, Ma, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344633/ https://www.ncbi.nlm.nih.gov/pubmed/25658509 http://dx.doi.org/10.3390/toxins7020423 |
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