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Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-A and acetylcholinesterase activity

BACKGROUND: Lipopolysaccharide (LPS)-mediated sickness behaviour is known to be a result of increased inflammatory cytokines in the brain. Inflammatory cytokines have been shown to mediate increases in brain excitation by loss of GABA(A)-mediated inhibition through receptor internalization or inacti...

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Detalles Bibliográficos
Autores principales: Ming, Zhi, Wotton, Caitlin A, Appleton, Robert T, Ching, John C, Loewen, Matthew E, Sawicki, Grzegorz, Bekar, Lane K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344755/
https://www.ncbi.nlm.nih.gov/pubmed/25890242
http://dx.doi.org/10.1186/s12974-015-0259-y