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Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-A and acetylcholinesterase activity
BACKGROUND: Lipopolysaccharide (LPS)-mediated sickness behaviour is known to be a result of increased inflammatory cytokines in the brain. Inflammatory cytokines have been shown to mediate increases in brain excitation by loss of GABA(A)-mediated inhibition through receptor internalization or inacti...
Autores principales: | Ming, Zhi, Wotton, Caitlin A, Appleton, Robert T, Ching, John C, Loewen, Matthew E, Sawicki, Grzegorz, Bekar, Lane K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344755/ https://www.ncbi.nlm.nih.gov/pubmed/25890242 http://dx.doi.org/10.1186/s12974-015-0259-y |
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