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RandomizEd controlled trial for pre-operAtive dose-escaLation BOOST in locally advanced rectal cancer (RECTAL BOOST study): study protocol for a randomized controlled trial

BACKGROUND: Treatment for locally advanced rectal cancer (LARC) consists of chemoradiation therapy (CRT) and surgery. Approximately 15% of patients show a pathological complete response (pCR). Increased pCR-rates can be achieved through dose escalation, thereby increasing the number patients eligibl...

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Detalles Bibliográficos
Autores principales: Burbach, JP Maarten, Verkooijen, Helena M, Intven, Martijn, Kleijnen, Jean-Paul JE, Bosman, Mirjam E, Raaymakers, Bas W, van Grevenstein, Wilhelmina MU, Koopman, Miriam, Seravalli, Enrica, van Asselen, Bram, Reerink, Onne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344756/
https://www.ncbi.nlm.nih.gov/pubmed/25888548
http://dx.doi.org/10.1186/s13063-015-0586-4