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RandomizEd controlled trial for pre-operAtive dose-escaLation BOOST in locally advanced rectal cancer (RECTAL BOOST study): study protocol for a randomized controlled trial
BACKGROUND: Treatment for locally advanced rectal cancer (LARC) consists of chemoradiation therapy (CRT) and surgery. Approximately 15% of patients show a pathological complete response (pCR). Increased pCR-rates can be achieved through dose escalation, thereby increasing the number patients eligibl...
Autores principales: | Burbach, JP Maarten, Verkooijen, Helena M, Intven, Martijn, Kleijnen, Jean-Paul JE, Bosman, Mirjam E, Raaymakers, Bas W, van Grevenstein, Wilhelmina MU, Koopman, Miriam, Seravalli, Enrica, van Asselen, Bram, Reerink, Onne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344756/ https://www.ncbi.nlm.nih.gov/pubmed/25888548 http://dx.doi.org/10.1186/s13063-015-0586-4 |
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