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A (1;19) translocation involving TCF3-PBX1 fusion within the context of a hyperdiploid karyotype in adult B-ALL: a case report and review of the literature

BACKGROUND: The t(1;19)(q23;p13), which can result in the TCF3-PBX1 chimeric gene, is one of the most frequent translocations in B-acute lymphoblastic leukemia (B-ALL) and is observed in both adult and pediatric populations at an overall frequency of 6%. It can occur in a balanced or unbalanced form...

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Detalles Bibliográficos
Autores principales: Tirado, Carlos A, Shabsovich, David, Yeh, Lei, Pullarkat, Sheeja T, Yang, Lynn, Kallen, Michael, Rao, Nagesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344763/
https://www.ncbi.nlm.nih.gov/pubmed/25729575
http://dx.doi.org/10.1186/s40364-015-0029-0