Cargando…

Ribosome Excursions during mRNA Translocation Mediate Broad Branching of Frameshift Pathways

Programmed ribosomal frameshifting produces alternative proteins from a single transcript. -1-frameshifting occurs on Escherichia coli’s dnaX mRNA containing a slippery sequence AAAAAAG and peripheral mRNA structural barriers. Here we reveal hidden aspects of the frameshifting process, including its...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Shannon, Wen, Jin-Der, Bustamante, Carlos, Tinoco, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344849/
https://www.ncbi.nlm.nih.gov/pubmed/25703095
http://dx.doi.org/10.1016/j.cell.2015.02.003