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Integrated allosteric regulation in the S. cerevisiae carbamylphosphate synthetase – aspartate transcarbamylase multifunctional protein

BACKGROUND: The S. cerevisiae carbamylphosphate synthetase – aspartate transcarbamylase multifunctional protein catalyses the first two reactions of the pyrimidine pathway. In this organism, these two reactions are feedback inhibited by the end product UTP. In the present work, the mechanisms of the...

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Detalles Bibliográficos
Autores principales: Serre, Valérie, Penverne, Bernadette, Souciet, Jean-Luc, Potier, Serge, Guy, Hedeel, Evans, David, Vicart, Patrick, Hervé, Guy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC434488/
https://www.ncbi.nlm.nih.gov/pubmed/15128434
http://dx.doi.org/10.1186/1471-2091-5-6