Phosphorylation of ribosomal protein S6 mediates compensatory renal hypertrophy

The molecular mechanism underlying renal hypertrophy and progressive nephron damage remains poorly understood. Here we generated congenic ribosomal protein S6 (rpS6) knockin mice expressing non-phosphorylatable rpS6 and found that uninephrectomy-induced renal hypertrophy was significantly blunted in...

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Detalles Bibliográficos
Autores principales: Xu, Jinxian, Chen, Jianchun, Dong, Zheng, Meyuhas, Oded, Chen, Jian-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344886/
https://www.ncbi.nlm.nih.gov/pubmed/25229342
http://dx.doi.org/10.1038/ki.2014.302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344886/
https://www.ncbi.nlm.nih.gov/pubmed/25229342
http://dx.doi.org/10.1038/ki.2014.302

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