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Long-term efficacy and safety of mipomersen in patients with familial hypercholesterolaemia: 2-year interim results of an open-label extension

AIMS: To evaluate the efficacy and safety of extended dosing with mipomersen in patients with familial hypercholesterolaemia (HC) taking maximally tolerated lipid-lowering therapy. METHODS AND RESULTS: A planned interim analysis of an ongoing, open-label extension trial in patients (n = 141) with fa...

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Detalles Bibliográficos
Autores principales: Santos, Raul D., Duell, P. Barton, East, Cara, Guyton, John R., Moriarty, Patrick M., Chin, Wai, Mittleman, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344956/
https://www.ncbi.nlm.nih.gov/pubmed/24366918
http://dx.doi.org/10.1093/eurheartj/eht549