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The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma

BACKGROUND: Although advanced esophageal squamous-cell carcinoma (ESCC) is treated using a multidisciplinary approach, outcomes remain unsatisfactory. The microenvironment of cancer cells has recently been shown to strongly influence the biologic properties of malignancies. We explored the effect of...

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Detalles Bibliográficos
Autores principales: Saito, Shin, Morishima, Kazue, Ui, Takashi, Hoshino, Hiroko, Matsubara, Daisuke, Ishikawa, Shumpei, Aburatani, Hiroyuki, Fukayama, Masashi, Hosoya, Yoshinori, Sata, Naohiro, Lefor, Alan K, Yasuda, Yoshikazu, Niki, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345039/
https://www.ncbi.nlm.nih.gov/pubmed/25884729
http://dx.doi.org/10.1186/s12885-015-1065-8