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Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria

Nuclear factor erythroid-derived 2-related factor 2 (Nrf2) was originally identified as a positive regulator of drug detoxifying enzyme gene expression during exposure to environmental electrophiles. Currently, Nrf2 is known to regulate the expression of hundreds of cytoprotective genes to counterac...

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Detalles Bibliográficos
Autores principales: Itoh, Ken, Ye, Peng, Matsumiya, Tomoh, Tanji, Kunikazu, Ozaki, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345178/
https://www.ncbi.nlm.nih.gov/pubmed/25759513
http://dx.doi.org/10.3164/jcbn.14-134