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Involvement of NADPH oxidases in suppression of cyclooxygenase-2 promoter-dependent transcriptional activities by sesamol

Cyclooxygenase-2 (COX-2) has been shown to play an important role in colon carcinogenesis. Moreover, one of the components of reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, NADPH oxidase 1 (NOX1), dominantly expressed in the colon, is implicated in the pathogenesis of colon can...

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Detalles Bibliográficos
Autores principales: Shimizu, Satomi, Ishigamori, Rikako, Fujii, Gen, Takahashi, Mami, Onuma, Wakana, Terasaki, Masaru, Yano, Tomohiro, Mutoh, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345183/
https://www.ncbi.nlm.nih.gov/pubmed/25759517
http://dx.doi.org/10.3164/jcbn.14-89