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Proteome response at the edge of protein aggregation

Proteins adopt defined structures and are crucial to most cellular functions. Their misfolding and aggregation is associated with numerous degenerative human disorders such as type II diabetes, Huntington's or Alzheimer's diseases. Here, we aim to understand why cells promote the formation...

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Detalles Bibliográficos
Autores principales: Sanchez de Groot, Natalia, Gomes, Ricardo A., Villar-Pique, Anna, Babu, M. Madan, Coelho, Ana Varela, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345283/
https://www.ncbi.nlm.nih.gov/pubmed/25673330
http://dx.doi.org/10.1098/rsob.140221