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Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription

In spite of prolonged and intensive treatment with combined antiretroviral therapy (cART), which efficiently suppresses plasma viremia, the integrated provirus of HIV-1 persists in resting memory CD4(+) T cells as latent infection. Treatment with cART does not substantially reduce the burden of late...

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Detalles Bibliográficos
Autores principales: Suzuki, Kazuo, Ahlenstiel, Chantelle, Marks, Katherine, Kelleher, Anthony D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345301/
https://www.ncbi.nlm.nih.gov/pubmed/25625613
http://dx.doi.org/10.1038/mtna.2014.67