Cargando…
Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription
In spite of prolonged and intensive treatment with combined antiretroviral therapy (cART), which efficiently suppresses plasma viremia, the integrated provirus of HIV-1 persists in resting memory CD4(+) T cells as latent infection. Treatment with cART does not substantially reduce the burden of late...
Autores principales: | Suzuki, Kazuo, Ahlenstiel, Chantelle, Marks, Katherine, Kelleher, Anthony D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345301/ https://www.ncbi.nlm.nih.gov/pubmed/25625613 http://dx.doi.org/10.1038/mtna.2014.67 |
Ejemplares similares
-
Controlling HIV-1: Non-Coding RNA Gene Therapy Approaches to a Functional Cure
por: Ahlenstiel, Chantelle L., et al.
Publicado: (2015) -
Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing
por: Suzuki, Kazuo, et al.
Publicado: (2013) -
Novel RNA Duplex Locks HIV-1 in a Latent State via Chromatin-mediated Transcriptional Silencing
por: Ahlenstiel, Chantelle, et al.
Publicado: (2015) -
Targeted Nanocarrier Delivery of RNA Therapeutics to Control HIV Infection
por: Agbosu, Esinam E., et al.
Publicado: (2022) -
Block and Lock HIV Cure Strategies to Control the Latent Reservoir
por: Ahlenstiel, Chantelle L., et al.
Publicado: (2020)