Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations

BACKGROUND: DNA polymerase ε (Pol ε) is essential for S-phase replication, DNA damage repair and checkpoint control in yeast. A pol2-Y831A mutation leading to a tyrosine to alanine change in the Pol ε active site does not cause growth defects and confers a mutator phenotype that is normally subtle b...

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Detalles Bibliográficos
Autores principales: Pavlov, Youri I, Maki, Satoko, Maki, Hisaji, Kunkel, Thomas A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC434536/
https://www.ncbi.nlm.nih.gov/pubmed/15163346
http://dx.doi.org/10.1186/1741-7007-2-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC434536/
https://www.ncbi.nlm.nih.gov/pubmed/15163346
http://dx.doi.org/10.1186/1741-7007-2-11

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