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Important biological information uncovered in previously unaligned reads from chromatin immunoprecipitation experiments (ChIP-Seq)
Establishing the architecture of gene regulatory networks (GRNs) relies on chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-Seq) methods that provide genome-wide transcription factor binding sites (TFBSs). ChIP-Seq furnishes millions of short reads that, after alignment,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345404/ https://www.ncbi.nlm.nih.gov/pubmed/25727450 http://dx.doi.org/10.1038/srep08635 |