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Important biological information uncovered in previously unaligned reads from chromatin immunoprecipitation experiments (ChIP-Seq)

Establishing the architecture of gene regulatory networks (GRNs) relies on chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-Seq) methods that provide genome-wide transcription factor binding sites (TFBSs). ChIP-Seq furnishes millions of short reads that, after alignment,...

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Detalles Bibliográficos
Autores principales: Ouma, Wilberforce Zachary, Mejia-Guerra, Maria Katherine, Yilmaz, Alper, Pareja-Tobes, Pablo, Li, Wei, Doseff, Andrea I., Grotewold, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345404/
https://www.ncbi.nlm.nih.gov/pubmed/25727450
http://dx.doi.org/10.1038/srep08635