Elevated germline mutation rate in teenage fathers

Men age and die, while cells in their germline are programmed to be immortal. To elucidate how germ cells maintain viable DNA despite increasing parental age, we analysed DNA from 24 097 parents and their children, from Europe, the Middle East and Africa. We chose repetitive microsatellite DNA that...

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Detalles Bibliográficos
Autores principales: Forster, Peter, Hohoff, Carsten, Dunkelmann, Bettina, Schürenkamp, Marianne, Pfeiffer, Heidi, Neuhuber, Franz, Brinkmann, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345458/
https://www.ncbi.nlm.nih.gov/pubmed/25694621
http://dx.doi.org/10.1098/rspb.2014.2898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345458/
https://www.ncbi.nlm.nih.gov/pubmed/25694621
http://dx.doi.org/10.1098/rspb.2014.2898

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