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Using constraints and their value for optimization of large ODE systems

We provide analytical tools to facilitate a rigorous assessment of the quality and value of the fit of a complex model to data. We use this to provide approaches to model fitting, parameter estimation, the design of optimization functions and experimental optimization. This is in the context where m...

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Detalles Bibliográficos
Autores principales: Domijan, Mirela, Rand, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345496/
https://www.ncbi.nlm.nih.gov/pubmed/25673300
http://dx.doi.org/10.1098/rsif.2014.1303