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Using constraints and their value for optimization of large ODE systems
We provide analytical tools to facilitate a rigorous assessment of the quality and value of the fit of a complex model to data. We use this to provide approaches to model fitting, parameter estimation, the design of optimization functions and experimental optimization. This is in the context where m...
Autores principales: | Domijan, Mirela, Rand, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345496/ https://www.ncbi.nlm.nih.gov/pubmed/25673300 http://dx.doi.org/10.1098/rsif.2014.1303 |
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