Complete remission of critical neurohistiocytosis by vemurafenib

OBJECTIVE: To describe a patient with life-threatening brainstem neurohistiocytosis who recovered completely upon targeted treatment with the V600E mutation-specific BRAF inhibitor vemurafenib. METHODS: We report clinical, histiologic, genetic, and sequential imaging findings, including fluorodeoxyg...

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Detalles Bibliográficos
Autores principales: Euskirchen, Philipp, Haroche, Julien, Emile, Jean-François, Buchert, Ralph, Vandersee, Staffan, Meisel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345630/
https://www.ncbi.nlm.nih.gov/pubmed/25745636
http://dx.doi.org/10.1212/NXI.0000000000000078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345630/
https://www.ncbi.nlm.nih.gov/pubmed/25745636
http://dx.doi.org/10.1212/NXI.0000000000000078

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