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Complete remission of critical neurohistiocytosis by vemurafenib
OBJECTIVE: To describe a patient with life-threatening brainstem neurohistiocytosis who recovered completely upon targeted treatment with the V600E mutation-specific BRAF inhibitor vemurafenib. METHODS: We report clinical, histiologic, genetic, and sequential imaging findings, including fluorodeoxyg...
Autores principales: | Euskirchen, Philipp, Haroche, Julien, Emile, Jean-François, Buchert, Ralph, Vandersee, Staffan, Meisel, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345630/ https://www.ncbi.nlm.nih.gov/pubmed/25745636 http://dx.doi.org/10.1212/NXI.0000000000000078 |
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