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Efficacy and safety of nebulized glycopyrrolate for administration using a high efficiency nebulizer in patients with chronic obstructive pulmonary disease

AIMS: To establish the dose−response for pharmacodynamics (bronchodilatation), safety and pharmacokinetics for a nebulized formulation of the long acting muscarinic antagonist glycopyrrolate (EP-101) with a high efficiency nebulizer in patients with chronic obstructive pulmonary disease (COPD). METH...

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Detalles Bibliográficos
Autores principales: Leaker, Brian R, Barnes, Peter J, Jones, C Richard, Tutuncu, Ahmet, Singh, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345959/
https://www.ncbi.nlm.nih.gov/pubmed/25243340
http://dx.doi.org/10.1111/bcp.12517