Pharmacokinetics and pharmacodynamics of peginterferon beta-1a in patients with relapsingremitting multiple sclerosis in the randomized ADVANCE study

AIMS: To evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of subcutaneous peginterferon beta-1a in patients with relapsing-remitting multiple sclerosis (RRMS) in the phase 3 ADVANCE study (n = 1512). METHODS: During year 1, patients were randomized (1:1:1) to placebo or peginterferon bet...

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Detalles Bibliográficos
Autores principales: Hu, Xiao, Cui, Yue, White, Joleen, Zhu, Ying, Deykin, Aaron, Nestorov, Ivan, Hung, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Pharmacokinetics Dynamic Relationships
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345961/
https://www.ncbi.nlm.nih.gov/pubmed/25265472
http://dx.doi.org/10.1111/bcp.12521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345961/
https://www.ncbi.nlm.nih.gov/pubmed/25265472
http://dx.doi.org/10.1111/bcp.12521

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