Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 ‘shared epitope’ alleles

INTRODUCTION: A hallmark of rheumatoid arthritis (RA) is the development of autoantibodies targeting proteins that contain citrulline. Anticitrullinated protein antibodies (ACPAs) are currently detected by the commercial cyclic citrullinated peptide (CCP) assay, which uses a mix of cyclised citrulli...

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Detalles Bibliográficos
Autores principales: Wagner, Catriona A, Sokolove, Jeremy, Lahey, Lauren J, Bengtsson, Camilla, Saevarsdottir, Saedis, Alfredsson, Lars, Delanoy, Michelle, Lindstrom, Tamsin M, Walker, Roger P, Bromberg, Reuven, Chandra, Piyanka E, Binder, Steven R, Klareskog, Lars, Robinson, William H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345988/
https://www.ncbi.nlm.nih.gov/pubmed/24297382
http://dx.doi.org/10.1136/annrheumdis-2013-203915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345988/
https://www.ncbi.nlm.nih.gov/pubmed/24297382
http://dx.doi.org/10.1136/annrheumdis-2013-203915

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