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Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 ‘shared epitope’ alleles
INTRODUCTION: A hallmark of rheumatoid arthritis (RA) is the development of autoantibodies targeting proteins that contain citrulline. Anticitrullinated protein antibodies (ACPAs) are currently detected by the commercial cyclic citrullinated peptide (CCP) assay, which uses a mix of cyclised citrulli...
Autores principales: | Wagner, Catriona A, Sokolove, Jeremy, Lahey, Lauren J, Bengtsson, Camilla, Saevarsdottir, Saedis, Alfredsson, Lars, Delanoy, Michelle, Lindstrom, Tamsin M, Walker, Roger P, Bromberg, Reuven, Chandra, Piyanka E, Binder, Steven R, Klareskog, Lars, Robinson, William H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345988/ https://www.ncbi.nlm.nih.gov/pubmed/24297382 http://dx.doi.org/10.1136/annrheumdis-2013-203915 |
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