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Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling

Despite the widespread application of silica nanoparticles (SiNPs) in industrial, commercial, and biomedical fields, their response to human cells has not been fully elucidated. Overall, little is known about the toxicological effects of SiNPs on the cardiovascular system. In this study, SiNPs with...

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Detalles Bibliográficos
Autores principales: Guo, Caixia, Xia, Yinye, Niu, Piye, Jiang, Lizhen, Duan, Junchao, Yu, Yang, Zhou, Xianqing, Li, Yanbo, Sun, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345992/
https://www.ncbi.nlm.nih.gov/pubmed/25759575
http://dx.doi.org/10.2147/IJN.S76114