Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing

BACKGROUND: The extent to which metastatic tumors further evolve by accumulating additional mutations is unclear and has yet to be addressed extensively using next-generation sequencing of high-grade serous ovarian cancer. METHODS: Eleven spatially separated tumor samples from the primary tumor and...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jung-Yun, Yoon, Jung-Ki, Kim, Boyun, Kim, Soochi, Kim, Min A, Lim, Hyeonseob, Bang, Duhee, Song, Yong-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346117/
https://www.ncbi.nlm.nih.gov/pubmed/25881093
http://dx.doi.org/10.1186/s12885-015-1077-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346117/
https://www.ncbi.nlm.nih.gov/pubmed/25881093
http://dx.doi.org/10.1186/s12885-015-1077-4

Ejemplares similares