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Naïve T-cells in Myelodysplastic Syndrome Display Intrinsic Human Telomerase Reverse Transcriptase (hTERT) Deficiency

Telomeres are specialized structures providing chromosome integrity during cellular division along with protection against premature senescence and apoptosis. Accelerated telomere attrition in patients with Myelodysplastic Syndrome (MDS) occurs by an undefined mechanism. Although the MDS clone origi...

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Detalles Bibliográficos
Autores principales: Yang, Lili, Mailloux, Adam, Rollison, Dana E., Painter, Jeffrey S., Maciejewski, Jaroslaw, Paquette, Ronald L., Loughran, Thomas P., McGraw, Kathy, Makishima, Hideki, Radhakrishnan, Rangasudhagar, Wei, Sheng, Ren, Xiubao, Komrokji, Rami, List, Alan F., Epling-Burnette, P.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346223/
https://www.ncbi.nlm.nih.gov/pubmed/23072779
http://dx.doi.org/10.1038/leu.2012.300