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Potential Small Guide RNAs for tRNase Z(L) from Human Plasma, Peripheral Blood Mononuclear Cells, and Cultured Cell Lines

Several pieces of evidence suggest that small RNA degradation products together with tRNase Z(L) appear to form another layer of the whole gene regulatory network. The degraded RNA such as a 5′-half-tRNA and an rRNA fragment function as small guide RNA (sgRNA) to guide the enzyme to target RNA. We w...

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Detalles Bibliográficos
Autores principales: Ninomiya, Sho, Kawano, Mitsuoki, Abe, Takashi, Ishikawa, Tatsuya, Takahashi, Masayuki, Tamura, Masato, Takahashi, Yoshiaki, Nashimoto, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346264/
https://www.ncbi.nlm.nih.gov/pubmed/25730316
http://dx.doi.org/10.1371/journal.pone.0118631