Molecular Dynamics Simulations of the Bacterial UraA H(+)-Uracil Symporter in Lipid Bilayers Reveal a Closed State and a Selective Interaction with Cardiolipin

The Escherichia coli UraA H(+)-uracil symporter is a member of the nucleobase/ascorbate transporter (NAT) family of proteins, and is responsible for the proton-driven uptake of uracil. Multiscale molecular dynamics simulations of the UraA symporter in phospholipid bilayers consisting of: 1) 1-palmit...

Descripción completa

Detalles Bibliográficos
Autores principales: Kalli, Antreas C., Sansom, Mark S. P., Reithmeier, Reinhart A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346270/
https://www.ncbi.nlm.nih.gov/pubmed/25729859
http://dx.doi.org/10.1371/journal.pcbi.1004123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346270/
https://www.ncbi.nlm.nih.gov/pubmed/25729859
http://dx.doi.org/10.1371/journal.pcbi.1004123

Ejemplares similares