Cargando…

The activity of cAMP-phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus

The cyclic AMP phosphodiesterases type 4 (PDE4s) are expressed in a cell specific manner, with intracellular targeting directed by unique N-terminal anchor domains. All long form PDE4s are phosphorylated and activated by PKA phosphorylation within their upstream conserved region 1 (UCR1). Here, we i...

Descripción completa

Detalles Bibliográficos
Autores principales: Byrne, Ashleigh M., Elliott, Christina, Hoffmann, Ralf, Baillie, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346272/
https://www.ncbi.nlm.nih.gov/pubmed/25680530
http://dx.doi.org/10.1016/j.febslet.2015.02.004