Over-Expression of Telomere Binding Factors (TRF1 & TRF2) in Renal Cell Carcinoma and Their Inhibition by Using SiRNA Induce Apoptosis, Reduce Cell Proliferation and Migration Invitro

Telomere binding factors viz. TRF1 and TRF2 are a part of sheltrin complex that are present exclusively at the ends of chromosomes. These factors play an important role in maintaining chromosomal integrity at the ends. However, their status and role are not clear in renal cell carcinoma (RCC). There...

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Detalles Bibliográficos
Autores principales: Pal, Deeksha, Sharma, Ujjawal, Singh, Shrawan Kumar, Kakkar, Nandita, Prasad, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346586/
https://www.ncbi.nlm.nih.gov/pubmed/25730259
http://dx.doi.org/10.1371/journal.pone.0115651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346586/
https://www.ncbi.nlm.nih.gov/pubmed/25730259
http://dx.doi.org/10.1371/journal.pone.0115651

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