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A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that the DENV-specific human mono...

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Detalles Bibliográficos
Autores principales: Fibriansah, Guntur, Tan, Joanne L., Smith, Scott A., de Alwis, Ruklanthi, Ng, Thiam-Seng, Kostyuchenko, Victor A., Jadi, Ramesh S., Kukkaro, Petra, de Silva, Aravinda M., Crowe, James E., Lok, Shee-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346626/
https://www.ncbi.nlm.nih.gov/pubmed/25698059
http://dx.doi.org/10.1038/ncomms7341