Cargando…

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that the DENV-specific human mono...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fibriansah, Guntur, Tan, Joanne L., Smith, Scott A., de Alwis, Ruklanthi, Ng, Thiam-Seng, Kostyuchenko, Victor A., Jadi, Ramesh S., Kukkaro, Petra, de Silva, Aravinda M., Crowe, James E., Lok, Shee-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346626/ https://www.ncbi.nlm.nih.gov/pubmed/25698059 http://dx.doi.org/10.1038/ncomms7341

Ejemplares similares

A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface
por: Fibriansah, Guntur, et al.
Publicado: (2014)

Antibody affinity versus dengue morphology influences neutralization
por: Fibriansah, Guntur, et al.
Publicado: (2021)

Natural Strain Variation and Antibody Neutralization of Dengue Serotype 3 Viruses
por: Wahala, Wahala M. P. B., et al.
Publicado: (2010)

Morphological Diversity and Dynamics of Dengue Virus Affecting Antigenicity
por: Fibriansah, Guntur, et al.
Publicado: (2021)

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C
por: Lim, Xin-Ni, et al.
Publicado: (2019)

CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever
por: Shu, Bo, et al.
Publicado: (2022)

Structural basis of Chikungunya virus inhibition by monoclonal antibodies
por: Zhou, Qun Fei, et al.
Publicado: (2020)

Dengue Viruses Are Enhanced by Distinct Populations of Serotype Cross-Reactive Antibodies in Human Immune Sera
por: de Alwis, Ruklanthi, et al.
Publicado: (2014)

Neutralization mechanism of a highly potent antibody against Zika virus
por: Zhang, Shuijun, et al.
Publicado: (2016)

Capsid protein is central to the birth of flavivirus particles
por: Tan, Ter Yong, et al.
Publicado: (2020)

Capsid protein structure in Zika virus reveals the flavivirus assembly process
por: Tan, Ter Yong, et al.
Publicado: (2020)

The Potent and Broadly Neutralizing Human Dengue Virus-Specific Monoclonal Antibody 1C19 Reveals a Unique Cross-Reactive Epitope on the bc Loop of Domain II of the Envelope Protein
por: Smith, Scott A., et al.
Publicado: (2013)

Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection
por: Collins, Matthew H., et al.
Publicado: (2017)

Release of Dengue Virus Genome Induced by a Peptide Inhibitor
por: Lok, Shee-Mei, et al.
Publicado: (2012)

Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4
por: Widman, Douglas G., et al.
Publicado: (2017)

Potent Neutralization Ability of a Human Monoclonal Antibody Against Serotype 1 Dengue Virus
por: Lu, Jiansheng, et al.
Publicado: (2018)

A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus
por: Xu, Meihui, et al.
Publicado: (2017)

Human dengue virus serotype 2 neutralizing antibodies target two distinct quaternary epitopes
por: Gallichotte, Emily N., et al.
Publicado: (2018)

Defining levels of dengue virus serotype-specific neutralizing antibodies induced by a live attenuated tetravalent dengue vaccine (TAK-003)
por: White, Laura J., et al.
Publicado: (2021)

Development and Characterization of a Reverse Genetic System for Studying Dengue Virus Serotype 3 Strain Variation and Neutralization
por: Messer, William B., et al.
Publicado: (2012)

Publisher Correction: A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus
por: Xu, Meihui, et al.
Publicado: (2018)

Conformational changes in intact dengue virus reveal serotype-specific expansion
por: Lim, Xin-Xiang, et al.
Publicado: (2017)

Regional Variation in Dengue Virus Serotypes in Sri Lanka and Its Clinical and Epidemiological Relevance
por: Jayadas, Tibutius T. P., et al.
Publicado: (2021)

Neutralization of Dengue Virus Serotypes by Sera from Dengue-Infected Individuals Is Preferentially Directed to Heterologous Serotypes and Not against the Autologous Serotype Present in Acute Infection
por: Auerswald, Heidi, et al.
Publicado: (2021)

Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus
por: Adams, Cameron, et al.
Publicado: (2023)

Tracking the polyclonal neutralizing antibody response to a dengue virus serotype 1 type-specific epitope across two populations in Asia and the Americas
por: Andrade, Daniela V., et al.
Publicado: (2019)

Emergence and Global Spread of a Dengue Serotype 3, Subtype III Virus
por: Messer, William B., et al.
Publicado: (2003)

A New Quaternary Structure Epitope on Dengue Virus Serotype 2 Is the Target of Durable Type-Specific Neutralizing Antibodies
por: Gallichotte, E. N., et al.
Publicado: (2015)

Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor
por: Chia, Wan Ni, et al.
Publicado: (2023)

Dengue Reporter Virus Particles for Measuring Neutralizing Antibodies against Each of the Four Dengue Serotypes
por: Mattia, Kimberly, et al.
Publicado: (2011)

Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype
por: Metz, Stefan W., et al.
Publicado: (2018)

Natural immunogenic properties of bioinformatically predicted linear B-cell epitopes of dengue envelope and pre-membrane proteins
por: Nadugala, Mahesha N., et al.
Publicado: (2021)

Unsuspected Dengue as a Cause of Acute Febrile Illness in Children and Adults in Western Nicaragua
por: Reller, Megan E., et al.
Publicado: (2016)

Induction of Neutralizing Antibodies against Four Serotypes of Dengue Viruses by MixBiEDIII, a Tetravalent Dengue Vaccine
por: Zhao, Hui, et al.
Publicado: (2014)

Phenotype and functionality of follicular helper T cells in patients with acute dengue infection
por: Wijesinghe, Ayesha, et al.
Publicado: (2020)

Cissampelos pareira Linn: Natural Source of Potent Antiviral Activity against All Four Dengue Virus Serotypes
por: Sood, Ruchi, et al.
Publicado: (2015)

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor
por: Dussupt, Vincent, et al.
Publicado: (2020)

Optimization and Validation of a Plaque Reduction Neutralization Test for the Detection of Neutralizing Antibodies to Four Serotypes of Dengue Virus Used in Support of Dengue Vaccine Development
por: Timiryasova, Tatyana M., et al.
Publicado: (2013)

Pediatric Measles Vaccine Expressing a Dengue Antigen Induces Durable Serotype-specific Neutralizing Antibodies to Dengue Virus
por: Brandler, Samantha, et al.
Publicado: (2007)

Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone
por: Gallichotte, Emily N., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_13pjrs95a78g40hjdv09ua5evj