Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo

Application of regulatory T cells (Tregs) in transplantation, autoimmunity and allergy has been extensively explored, but how Foxp3 and Treg stability is regulated in vivo is incompletely understood. Here, we identify a requirement for Deltex1 (DTX1), a contributor to T-cell anergy and Foxp3 protein...

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Detalles Bibliográficos
Autores principales: Hsiao, Huey-Wen, Hsu, Tzu-Sheng, Liu, Wen-Hsien, Hsieh, Wan-Chen, Chou, Ting-Fang, Wu, Yu-Jung, Jiang, Si-Tse, Lai, Ming-Zong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346631/
https://www.ncbi.nlm.nih.gov/pubmed/25695215
http://dx.doi.org/10.1038/ncomms7353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346631/
https://www.ncbi.nlm.nih.gov/pubmed/25695215
http://dx.doi.org/10.1038/ncomms7353

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