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Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo

Application of regulatory T cells (Tregs) in transplantation, autoimmunity and allergy has been extensively explored, but how Foxp3 and Treg stability is regulated in vivo is incompletely understood. Here, we identify a requirement for Deltex1 (DTX1), a contributor to T-cell anergy and Foxp3 protein...

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Detalles Bibliográficos
Autores principales:	Hsiao, Huey-Wen, Hsu, Tzu-Sheng, Liu, Wen-Hsien, Hsieh, Wan-Chen, Chou, Ting-Fang, Wu, Yu-Jung, Jiang, Si-Tse, Lai, Ming-Zong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346631/ https://www.ncbi.nlm.nih.gov/pubmed/25695215 http://dx.doi.org/10.1038/ncomms7353

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