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The HDAC Inhibitor Vorinostat Diminishes the In Vitro Metastatic Behavior of Osteosarcoma Cells

Osteosarcoma (OS) is the most common primary malignancy of bone and affects patients in the first two decades of life. The greatest determinant of survival is the presence of pulmonary metastatic disease. The role of epigenetic regulation in OS, specifically the biology of metastases, is unknown. Ou...

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Detalles Bibliográficos
Autores principales: Mu, Xiaodong, Brynien, Daniel, Weiss, Kurt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346695/
https://www.ncbi.nlm.nih.gov/pubmed/25785263
http://dx.doi.org/10.1155/2015/290368