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Promoter Hypermethylation of Tumour Suppressor Genes as Potential Biomarkers in Colorectal Cancer
Colorectal cancer (CRC) is a common malignancy and the fourth leading cause of cancer deaths worldwide. It results from the accumulation of multiple genetic and epigenetic changes leading to the transformation of colon epithelial cells into invasive adenocarcinomas. In CRC, epigenetic changes, in pa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346847/ https://www.ncbi.nlm.nih.gov/pubmed/25622259 http://dx.doi.org/10.3390/ijms16022472 |