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Differential Salt-Induced Dissociation of the p53 Protein Complexes with Circular and Linear Plasmid DNA Substrates Suggest Involvement of a Sliding Mechanism

A study of the effects of salt conditions on the association and dissociation of wild type p53 with different ~3 kbp long plasmid DNA substrates (supercoiled, relaxed circular and linear, containing or lacking a specific p53 binding site, p53CON) using immunoprecipitation at magnetic beads is presen...

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Detalles Bibliográficos
Autores principales: Šebest, Peter, Brázdová, Marie, Fojta, Miroslav, Pivoňková, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346886/
https://www.ncbi.nlm.nih.gov/pubmed/25647416
http://dx.doi.org/10.3390/ijms16023163