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MRS of Brain Metabolite Levels Demonstrates the Ability of Scavenging of Excess Brain Glutamate to Protect against Nerve Agent Induced Seizures

This study describes the use of in vivo magnetic resonance spectrocopy (MRS) to monitor brain glutamate and lactate levels in a paraoxon (PO) intoxication model. Our results show that the administration of recombinant glutamate-oxaloacetate transaminase (rGOT) in combination with oxaloacetate (OxAc)...

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Detalles Bibliográficos
Autores principales: Ruban, Angela, Biton, Inbal E., Markovich, Arik, Mirelman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346891/
https://www.ncbi.nlm.nih.gov/pubmed/25648322
http://dx.doi.org/10.3390/ijms16023226